This Korean Skincare Ingredient Could Help Fight Deadly Superbugs

Researchers at the University of Kent and UCL found that madecassic acid, a compound from Centella asiatica used in Korean skincare, can inhibit antibiotic-resistant E. coli.

The compound works by targeting the cytochrome bd respiratory complex, a bacterial protein system linked to survival under stress.

Modified versions of madecassic acid showed even stronger antibacterial activity, suggesting a promising starting point for new drugs.

The finding matters because antibiotic resistance is a major global health threat, and a plant-derived ingredient may offer a safer path to future antimicrobials.