“Totally Unexpected” – Scientists Discover Pancreatic Cancer’s Fatal Addiction

Scientists found that low Mic60 damages mitochondria in pancreatic cancer cells, triggering an inflammatory TLR3/TRAF6 pathway.

The tumors appear to depend on leaked mitochondrial double-stranded RNA to keep that inflammation alive.

Blocking the pathway killed cancer cells and stopped tumor growth in mouse models.

The work points to a new treatment target for a cancer with few effective options.