An Early Clue to Alzheimer's May Appear as Young as 45, Study Finds

Researchers in the long-running Dunedin Study found that by age 45, higher pTau181 levels were linked to self-reported memory and thinking concerns.

The findings suggest Alzheimer’s-related changes may be detectable in midlife, before standard tests or brain scans show clear problems.

If confirmed, these early signals could support prevention strategies and improve the timing of treatments when they are most effective.