Natural Component From Licorice Shows Promise for Treating Inflammatory Bowel Disease

Researchers used a human stem cell-derived intestinal organoid to model IBD-like inflammation and screen about 3,500 compounds.

They identified glycyrrhizin, a compound from black licorice, as a candidate that reduced intestinal cell death and inflammation.

The effect was also confirmed in mice, suggesting possible therapeutic potential for inflammatory bowel disease.

The study highlights a scalable human tissue model that could speed up drug discovery, though human trials are still needed.