World MS Day: Immune Cell Discovery Might Explain Multiple Sclerosis at Its Worst

A Dutch study found fat-laden foamy microglia in post-mortem brains of people with secondary progressive MS.

These immune cells were linked to more severe disease, different lesion biology, and weaker tissue repair.

In mice, blocking a microglial enzyme improved healing, hinting at a new treatment strategy.

The results point to microglial fat metabolism as a possible target for severe multiple sclerosis.