Scientists Found What May Be Keeping the Alzheimer’s Brain Awake

University of Kentucky researchers found that microglia, not amyloid plaques alone, were driving sleep loss in Alzheimer’s-like mouse models.

Reducing these immune cells with pexidartinib restored more than two hours of sleep per day.

EEG analysis also uncovered brain-wave patterns that could support simpler, noninvasive screening for Alzheimer’s-related sleep disruption.