Scientists Teach AI To Think Like a Professional Chemist

EPFL researchers developed Synthegy, an AI framework that blends retrosynthesis search with large language models.

It can interpret plain-language strategy prompts, rank synthetic routes, and evaluate reaction mechanisms.

In tests, it aligned closely with expert judgments and often picked strategically preferred, plausible pathways.

The system could make synthesis planning faster and more intuitive for drug and materials discovery.