Scientists Just Captured Killer T Cells in Action Inside Tumors

Researchers at UNIGE and CHUV used cryo-expansion microscopy to image killer T cells attacking cancer cells in near-native 3D detail.

The study revealed a dome-like immune synapse and a more varied organization of cytotoxic granules than previously seen.

The approach worked in both lab samples and human tumor tissue, offering a sharper view of how T cells kill with precision.

The findings could help improve immuno-oncology strategies by clarifying the cellular machinery behind anti-tumor immunity.