Scientists Discover How to Stop Vision Loss Before It Starts

Researchers screened over 2,700 compounds in 20,000 human retinal organoids to find molecules affecting cone survival.

Inhibition of casein kinase 1 and two kinase inhibitors preserved cone photoreceptors across stress conditions.

Protective effects were confirmed in a mouse model and a comprehensive dataset of results was published.

The findings identify new drug targets and reveal some compound classes that can harm cone cells.