Scientists Just Rewrote Biology: “Hidden” Mechanism Could Transform Diabetes Treatment

WEHI researchers discovered a new pathway where ubiquitin directly regulates glycogen storage.

This is the first evidence in humans that stored sugar can be controlled directly, not only through hormones.

The finding overturns a long-standing view of metabolism and may open new treatment options for diabetes and glycogen-related diseases.

Published in Nature, the work could help target glycogen buildup at its source in liver, heart, and rare genetic disorders.